Zyban and Weight Loss

There have been clinical trials of Burproprion that show that this active ingredient in Zyban and Wellbutrin may very well contribute to increased weight loss when part of a lowered calorie diet coupled with exercise.

And while these trials may show that Bupropion can help lose weight, Zyban is a lower dosage pill than what was being taken in these trials.  The trials were based on higher dosages, in the range prescribed as Wellbutrin.

Zyban weight loss claims are few and far between. Mainly because Zyban is taken as a smoking cessation aid, and many people gain weight when they quit smoking.
Now, some of the trials for Zyban show that those who took Zyban had decreased weight gain...

So, Yeah,
It is possible that Zyban and weight loss could go together.
But since your doctor should only be prescribing this medication for smoking cessation, the odds of seeing weight loss on Zyban are decreased.

In fact, weight loss on Zyban is considered a potential Side Effect and the instructions that are given to you with your prescription specifically mention that if you experience weight loss on Zyban, then you should consult with your physician immediately.

The potential side effects of Bupropion are great enough, that even the FDA feels that this is a dangerous enough substance that it should only be used under a doctor's care.

Of course, if you find a doctor that would prescribe Zyban for weight loss...
My recommendation would to be to run the other way.

While weight loss by taking Zyban is possible, there is no substitute for a decreased calorie and increased exercise regiment for weight loss.